Cognitive Remediation Journal, 2015 (vol. 4), issue 1
Original work
Animal Models of Schizophrenia with a Focus on Models Targeting NMDA Receptors
Svojanovská M., Stuchlík A.
Cognitive Remediation Journal 2015, 4(1):3-18 | DOI: 10.5507/crj.2015.001 
Schizophrenia is a serious and often devastating disease, affecting approximately 1% of worldwide population. Animal models represent a suitable way for investigating serious brain diseases in preclinical research. Animal models of schizophrenia can be generally divided into several categories that include pharmacological, genetic and neurodevelopmental models. Pharmacological models are usually based on application of specific receptor ligands for neurotransmitters. Genetic models are created by genetic manipulations (mutations; often in laboratory mice). Neurodevelopmental models are induced by manipulations in early stages of life of the laboratory...
Go/NoGo continuous performance task in the psychophysiological research
Andrea Mestanikova, Igor Ondrejka, Michal Mestanik, Igor Hrtanek, Eva Snircova, Ingrid Tonhajzerova
Cognitive Remediation Journal 2015, 4(1):19-29 | DOI: 10.5507/crj.2015.002
Introduction: Go/NoGo continuous performance task (CPT) is a neuropsychological test designed for measurement of attention and impulsivity and very often associated with attention deficit hyperactivity disorder (ADHD). The aim of this study was to provide current view of test with its application in future psychophysiological research and clinical practise.Methods: The studies regarding CPT were collected using scientific databases (PUBMed, Medline, SCOPUS). The heart rate variability (HRV) as an index of parasympathetic activity and electrodermal activity (EDA) as a noninvasive index of sympathetic arousal were applied in ADHD and depression during...