Cognitive Remediation Journal 2016, 5(1):3-15 | DOI: 10.5507/crj.2016.001

EEG biofeedback in patients with schizophrenia: another possibility to influence cognitive deficit?

Veronika Voráčková, Filip Španiel, Pavel Mohr, Mabel Rodriguez
Národní ústav duševního zdraví, Topolová 748, Klecany

Přehledový článek pojednává o aplikaci EEG-biofeedbacku u pacientů se schizofrenií se zaměřením na oblast kognitivních funkcí. EEG-biofeedback je forma neurofeedbacku, při kterém dochází k záměrnému ovlivňování mozkové aktivity prostřednictvím jejího reálného záznamu za pomoci EEG. Pacient je aktivním účastníkem při léčbě, což hraje svou roli při kognitivní remediaci. Je zde předkládán přehled abnormalit v oblasti EEG záznamů u pacientů se schizofrenií. Současně předkládáme podrobný popis dosavadních studií věnujících se aplikaci EEG-biofeedbacku u schizofrenie i jiných neuropsychiatrických poruch a pozornost je věnována i nedostatkům těchto studí. V závěru se snažíme shrnout přínosy aplikace této metody.

This paper reviews the application of the EEG-biofeedback in the treatment of schizophrenia, with a focus on cognitive function. EEG biofeedback is a type of neurofeedback, that allows the deliberate influence brain activity through real EEG record. The patient is an active participant in his own treatment, which is an important fact for cognitive remediation. We present the summary of abnormalities in EEG record in schizophrenia patients. We also bring forward detailed description of up to date studies using the EEG-biofeedback in schizophrenia and other neuropsychiatric disorders, and we focus on the drawbacks of these studies. At the end of the review we try to summarize the benefits of EEG-biofeedback.

Keywords: biofeedback, neurofeedback, electroencephalography, schizophrenia, cognitive remediation

Received: May 10, 2016; Accepted: August 8, 2016; Published: March 31, 2016  Show citation

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Voráčková V, Španiel F, Mohr P, Rodriguez M. EEG biofeedback in patients with schizophrenia: another possibility to influence cognitive deficit? Cogn. Remediat. J. 2016;5(1):3-15. doi: 10.5507/crj.2016.001.
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    References

    1. AMANN, B. L., POGARELL, O., MERGL, R., JUCKEL, G., GRUNZE, H., MULERT, C. ET AL. (2003): EEG abnormalities associated with antipsychotics: A comparison of quetiapine, olanzapine, haloperidol and healthy subjects. Human Psychopharmacology: Clinical And Experimental 18(8), 641-646. Go to original source...
    2. ARNS, M., HEINRICH, H., & STREHL, U. (2014). Evaluation of neurofeedback in ADHD: The long and winding road. Biological Psychology, 95108-115. Go to original source...
    3. BARES, M., NOVAK, T., BRUNOVSKY, M., KOPECEK, M., STOPKOVA, P., KRAJCA, V., & HÖSCHL, C. (2012). The change of QEEG prefrontal cordance as a response predictor to antidepressive intervention in bipolar depression. A pilot study. J Psychiatr Res, 46(2), 219-225. Go to original source...
    4. BEGIĆ, D., HOTUJAC, L., JOKIĆ BEGIĆ, N. (2000): Quantitative EEG in 'positive' and 'negative' schizophrenia. Acta Psychiatr Scand101(4), 307-311. Go to original source...
    5. BOČKOVÁ M., REKTOR I. (2009): Desynchronizace a synchronizace EEG rytmů. Neurologie pro praxi 10(4), 242-254.
    6. BORA, E., MURRAY, R. M. (2014): Meta-analysis of cognitive deficits in ultra-high risk to psychosis and first-episode Psychosis: Do the cognitive deficits progress over, or after, the onset of psychosis?. Schizophr Bull 40(4), 744-755. Go to original source...
    7. BOWIE, C. R., GROSSMAN, M., GUPTA, M., OYEWUMI, L. K., & HARVEY, P. D. (2014). Cognitive remediation in schizophrenia: efficacy and effectiveness in patients with early versus long-term course of illness. Early Interv Psychiatry, 8(1), 32-38. Go to original source...
    8. CLEMENTZ, B. A., SPONHEIM, S. R., IACONO, W. G., BEISER, M. (1994): Resting EEG in first-episode schizophrenia patients, bipolar psychosis patients, and their first-degree relatives. Psychophysiology 31(5), 486-494. Go to original source...
    9. COTHRAN, T. P., LARSON, J. E. (2012): Brain-computer interface technology for schizophrenia. J Dual Diagn8(4), 337-340. Go to original source...
    10. DESTE, G., BARLATI, S., CACCIANI, P., DEPERI, L., POLI, R., SACCHETTI, E., & VITA, A. (2015). Persistence of effectiveness of cognitive remediation interventions in schizophrenia: A 1-year follow-up study. Schizophr Res, 161(2-3). Go to original source...
    11. EL-MISSIRY, A., ELBATRAWY, A., EL MISSIRY, M., MONEIM, D. A., ALI, R., & ESSAWY, H. (2015). Comparing cognitive functions in medication adherent and non-adherent patients with schizophrenia. J Psychiatr Res, 70106-112. Go to original source...
    12. FATOUROS-BERGMAN, H., CERVENKA, S., FLYCKT, L., EDMAN, G., FARDE, L. (2014): Meta-analysis of cognitive performance in drug-naïve patients with schizophrenia. Schizophr Res 158(1-3), 156-162. Go to original source...
    13. FIORAVANTI M., BIANCHI V., CINTI, M. E. (2012): Cognitive deficits in schizophrenia: an updated metanalysis of the scientific evidence. BMC Psychiatry 12(1): 64-83. Go to original source...
    14. FIORAVANTI M., CARLONE O., VITALE B., CINTI, M. E., CLARE L. (2005): A Meta-Analysis of Cognitive Deficits in Adults with a Diagnosis of Schizophrenia. Neuropsychol Rev 15(2): 73-95. Go to original source...
    15. FITZGERALD, P. B., & DASKALAKIS, Z. J. (2008). A Review of Repetitive Transcranial Magnetic Stimulation Use in the Treatment of Schizophrenia. Can J Psychiatry, 53(9), 567-576. Go to original source...
    16. GRUZELIER, J., HARDMAN, E., WILD, J., ZAMAN, R. (1999): Learned control of slow potential interhemispheric asymmetry in schizophrenia. International Journal of Psychophysiology 34(3), 341-348. Go to original source...
    17. HAMMOND, D. (2005). Neurofeedback Treatment of Depression and Anxiety. J Adult Dev, 12(2/3), 131-137. Go to original source...
    18. HARVEY P. D., GOLD J. M. (1993): Cognitive deficits in schizophrenia. Psychiatr Clin North Am 16(2):295-312. Go to original source...
    19. HOY, K. E., ARNOLD, S. L., EMONSON, M. L., DASKALAKIS, Z. J., FITZGERALD, P. B. (2014): An investigation into the effects of tDCS dose on cognitive performance over time in patients with schizophrenia. Schizophr Res 155(1-3), 96-100. Go to original source...
    20. ITIL, T. M., SALETU, B., DAVIS, S., & ALLEN, M. (1974). Stability studies in.sehizophrenies and normals using computer-analyzed EEG. Biological Psychiatry, 8, 321-335.
    21. JALILI, M., MEULI, R., DO, K. Q., HASLER, M., CROW, T. J., KNYAZEVA, M. G. (2010): Attenuated asymmetry of functional connectivity in schizophrenia: A high-resolution EEG study. Psychophysiology 47(4), 706-716. Go to original source...
    22. KANDEL, E.R. (2001): The molecular biology of memory storage: a dialogue between genes and synapses. Science 294,1030-1038. Go to original source...
    23. KEEFE, R. E., BILDER, R. M., DAVIS, S. M., HARVEY, P. D., PALMER, B. W., GOLD, J. M. ET AL. (2007): Neurocognitive effects of antipsychotic medications in patients with chronic schizophrenia in the CATIE trial. Arch Gen Psychiatry 64(6), 633-647. Go to original source...
    24. KEMALI, D., GALDERISI, S., MAJ, M., MUCCI, A., GREGORIO, M. D., BUCCI, P. (1992): Computerized EEG topography findings in schizophrenic patients before and after haloperidol treatment. International Journal of Psychophysiology 13(3), 283-290. Go to original source...
    25. KOPŘIVOVÁ, J., CONGEDO, M., RASZKA, M., PRAŠKO, J., BRUNOVSKÝ, M., HORÁČEK, J. (2013): Prediction of treatment response and the effect of independent component neurofeedback in obsessive-compulsive disorder: A randomized, sham-controlled, double-blind study. Neuropsychobiology 67(4), 210-223. Go to original source...
    26. LOUGHLAND, C. M., LEWIN, T. J., CARR, V. J., SHEEDY, J., & HARRIS, A. W. (2007). RBANS neuropsychological profiles within schizophrenia samples recruited from non-clinical settings. Schizophr Res, 89(1-3), 232-242. Go to original source...
    27. LUBAR, J. F. (1991): Discourse on the development of EEG diagnostics and biofeedback for attention-deficit/hyperactivity disorders. Biofeedback Self Regul16(3), 201-225. Go to original source...
    28. MANCHANDA, R., NORMAN, R., MALLA, A., HARRICHARAN, R., NORTHCOTT, S. (2008): EEG abnormalities and 3-year outcome in first episode psychosis. Acta Psychiatr Scand117(4), 277-282. Go to original source...
    29. MANCHANDA, R., NORMAN, R., MALLA, A., HARRICHARAN, R., NORTHCOTT, S., RICHARD, J. (2014): Electroencephalographic abnormalities and 5-year outcome in first-episode psychosis. Can J Psychiatry 59(5), 285-288. Go to original source...
    30. MCGURK, S. R., MUESER, K. T., DEROSA, T. J., WOLFE, R. (2009): Work, recovery, and comorbidity in schizophrenia: A randomized controlled trial of cognitive remediation. Schizophr Bull 35(2), 319-335. Go to original source...
    31. MESHOLAM-GATELY, R. I., GIULIANO, A. J., GOFF, K. P., FARAONE, S. V., SEIDMAN, L. J. (2009): Neurocognition in first-episode schizophrenia: A meta-analytic review. Neuropsychology 23(3), 315-336. Go to original source...
    32. MOHR P, RODRIGUEZ M, NOVÁK T, KOPEČEK M, HORÁČEK J, HENDRYCHOVÁ Y, ZÁLESKÝ R, KAWACIUKOVÁ R, PREISS M, SEIFERTOVÁ D. Repetitivní transkraniální magnetická stimulace a rehabilitace kognitivních funkcí u schizofrenie (Repetitive transcranial magnetic stimulation and cognitive rehabilitation in schizophrenia). Psychiatrie, 2006; 10(1): 7-15.
    33. O'REILLY, K., DONOHOE, G., O'SULLIVAN, D., COYLE, C., MULLANEY, R., O'CONNELL, P., &... KENNEDY, H. G. (2016). Study protocol: a randomised controlled trial of cognitive remediation for a national cohort of forensic mental health patients with schizophrenia or schizoaffective disorder. BMC Psychiatry, 161-13. Go to original source...
    34. RAMOS, J., CERDÁN, L. F., GUEVARA, M. A., AMEZCUA, C., SANZ, A. (2001): Abnormal EEG patterns in treatment-resistant schizophrenic patients. Int J Neurosci109(1-2), 47-59. Go to original source...
    35. RITSNER, M. S. (2007): Predicting quality of life impairment in chronic schizophrenia from cognitive variables. Qual Life Res16(6), 929-937. Go to original source...
    36. SAVILLA, K., KETTLER, L., GALLETLY, C. (2008): Relationships between cognitive deficits, symptoms and quality of life in schizophrenia. Australian And New Zealand Journal Of Psychiatry 42(6), 496-504. Go to original source...
    37. SAYKIN, A. J., SHTASEL, D. L., GUR, R. E., KESTER, D. B., MOZLEY, L. H., STAFINIAK, P., & GUR, R. C. (1994). Neuropsychological deficits in neuroleptic naive patients with first-episode schizophrenia. Arch Gen Psychiatry, 51(2), 124-131. Go to original source...
    38. SHRIVASTAVA, A., DE SOUSA, A., JOHNSTON, M., SHAH, N., STITT, L. (2014): Electroencephalographic abnormality and clinical response in patients with first-episode schizophrenia treated with clozapine. J Psychiatry 15(1), 30-38.
    39. SCHNEIDER, F., ROCKSTROH, B., HEIMANN, H., LUTZENBERGER, W., MATTES, R., ELBERT, T. ET AL. (1992): Self-regulation of slow cortical potentials in psychiatric patients: Schizophrenia. Biofeedback Self Regul17(4), 277-292. Go to original source...
    40. SCHNEIDER, S. J., POPE, A. T. (1982): Neuroleptic-like electroencephalographic changes in schizophrenics through biofeedback. Biofeedback Self Regul7(4), 479-490. Go to original source...
    41. SCHOENBERG, P. A., SIERRA, M., DAVID, A. S. (2012): Psychophysiological investigations in depersonalization disorder and effects of electrodermal biofeedback. Journal Of Trauma & Dissociation 13(3), 311-329. Go to original source...
    42. SIEPMANN, M., AYKAC, V., UNTERDÖRFER, J., PETROWSKI, K., MEUCK-WEYMANN, M. (2008): A pilot study on the effects of heart rate variability biofeedback in patients with depression and in healthy subjects. Appl Psychophysiol Biofeedback 33, 195-201. Go to original source...
    43. SPENCER KM, NESTOR PG, NIZNIKIEWICZ MA, SALISBURY DF, SHENTON ME, MCCARLEY RW (2003). Abnormal neural synchrony in schizophrenia. J Neurosci 23: 7407-7411. Go to original source...
    44. SPENCER KM, NESTOR PG, PERLMUTTER R, NIZNIKIEWICZ MA, KLUMPMC, FRUMIN M ET AL (2004). Neural synchrony indexes disordered perception and cognition in schizophrenia. ProcNatl Acad Sci USA 101: 17288-17293. Go to original source...
    45. SPONHEIM, S. R., CLEMENTZ, B. A., IACONO, W. G., BEISER, M. (1994): Resting EEG in first-episode and chronic schizophrenia. Psychophysiology 31(1), 37-43. Go to original source...
    46. SURMELI, T., ERTEM, A., ERALP, E., KOS, I. H. (2012): Schizophrenia and the efficacy of qEEG-guided neurofeedback treatment: A clinical case series. Clinical EEG and Neuroscience 43(2), 133-144. Go to original source...
    47. ŠÓŠ, P. (2003): Měření, sledování a vyhodnocení nových neurofyziologických indikátorů u vybraných psychiatrických onemocnění. Charles University in Prague, Czech Republic.
    48. THOMPSON, L., THOMPSON, M. (1998). Neurofeedback combined with training in metacognitive strategies: Effectiveness in students with ADD. Appl Psychophysiol Biofeedback, 23(4), 243-263. Go to original source...
    49. THOMPSON, L., THOMPSON, M., & REID, A. (2010). Functional Neuroanatomy and the Rationale for Using EEG Biofeedback for Clients with Asperger's Syndrome. Applied Psychophysiology & Biofeedback, 35(1), 39-61. Go to original source...
    50. THOMPSON, L., THOMPSON, M., & REID, A. (2010). Neurofeedback Outcomes in Clients with Asperger's Syndrome. Applied Psychophysiology & Biofeedback, 35(1), 63-81. Go to original source...
    51. VAN ERP, T. G., PREDA, A., TURNER, J. A., CALLAHAN, S., CALHOUN, V. D., BUSTILLO, J. R., &... POTKIN, S. G. (2015). Neuropsychological profile in adult schizophrenia measured with the cminds. Psychiatry Res. Go to original source...
    52. WALKER, J. E., LAWSON, R. (2013): FB02 beta training for drugresistant depression - a new protocol that usually reduces depression and keeps it reduced. J Neurother, 17(3), 198-200. Go to original source...
    53. WILK, CH. M., GOLD, J. M., MCMAHON, R. P., HUMER, K., IANNONE, V. N., BUCHANAN, R.W. (2005): No, it is not possible to be schizophrenic yet neuropsychologically normal. Neuropsychology 9(6), 778-786. Go to original source...
    54. Woodward ND, Purdon SE, Meltzer HY, Zald DH. A meta-analysis of neuropsychological change to clozapine, olanzapine, quetiapine, and risperidone in schizophrenia. Int J Neuropsychopharmacology 2005; 8: 457-472. Go to original source...
    55. WYKES, T., HUDDY, V., CELLARD, C., MCGURK, S. R., CZOBOR, P. (2011): A meta-analysis of cognitive remediation for schizophrenia: Methodology and effect sizes. Am J Psychiatry 168(5), 472-485. Go to original source...
    56. XIAOPENG, D., GAOHUA, W., LIFANG, Z., XINFENG, Z., MEI, Y., GANGYA, H. ET AL. (2014): Randomized controlled trial of adjunctive EEG-biofeedback treatment of obsessive-compulsive disorder. Shanghai Archives Of Psychiatry 26(5), 272-279.

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